Outsmarting menopause

Solgen® is a unique and natural isoflavone ingredient from Non-GMO soybeans

Midlife woman’s body

The arrival of menopause marks the beginning of a new stage in the midlife women lives. Although it is an inescapable moment, it can be quite an emotional challenge for many women. Whilst the progressive withdrawal of menstruation is accompanied by the uncomfortable symptoms of menopause, the process is even more difficult.

Experiencing certain discomforts at menopause is normal and the supplementation with Solgen® contributes to minimising the symptoms.

Cardiovascular risk increases with the decline in estrogen production after menopause.

Solgen® influences nitric oxide-dependent vasorelaxation, protecting postmenopausal women against endothelial dysfunction.

These are the most common symptoms of menopause, affecting 75-85% of women, due to the lowered levels of estrogen.

Solgen® is the unique soy isoflavones approved for the treatment of hot flashes during menopause.

For post-menopausal women, acceleration of chronologic aging is enhanced by the loss of estrogen, which causes a rapid loss of collagen during the first 5 years after menopause.

Solgen® has been proven to be an effective dietary supplement in improving the appearance and condition of the skin in post-menopausal women.

Memory loss, mood swings and sleep problems increase during the menopause transition.

Solgen® enhances cognitive processes which appear dependent on estrogen activation.

Changes in menstrual flow, inconsistency and frequency are the hallmarks of menopause.
Lowered estrogen levels cause thinning of the vaginal lining, and elasticity, blood flow and lubrication are reduced; uncomfortable symptoms that lead to a lack of arousal.

Supplementation with Solgen® contributes to minimising these symptoms.

Changes in hormonal patterns during menopause may explain the increase in the prevalence of urinary incontinence (UI) among women. UI is a significant health problem with considerable social and economic impact.

Solgen® reduces morphological changes that contribute to UI, such as increased collagen connective tissue and degenerative changes to the bladder.

Estrogen deficiency accelerates the effects of ageing on bone by decreasing defence against oxidative stress, that leads to body aches, stiffness and joint pain.

Solgen® protects the adult skeleton against bone loss by slowing the rate of bone remodelling and by maintaining a focal balance between bone formation and resorption.

As estrogen lowers, women are more prone to gain weight during the menopause transition averaging about a 5 lb weight gain. There are risks associated with weight gain which include high blood pressure, heart diseases and diabetes.

Solgen® increases a woman’s resting metabolic rate supporting a benefit in not gaining weight.

Isoflavones in ancient tradition

Japanese women have the world's longest average life expectancy and one of the lowest incidence rates of hormone-dependent diseases such as breast and ovarian cancers or coronary heart disease.

Likewise, Asian women have a lower incidence of climacteric-related disorders, such as hot flashes.

Researchers have found that the explanation for this might be attributed to the soy consumption that often begins in utero and continues throughout their lifespan.

Beyond pharmaceutical soybean isoflavones

SOLGEN® is the unique soybean isoflavones approved for the treatment of hot flashes during menopause (eCTD-DMF available).

– The SOLGEN® soybean isoflavones profile mimics the human body’s natural estrogen.

– SOLGEN® contains high levels of Genistin and Genistein in a ratio of glycosides conjugates and aglycones that matches the profile of isoflavones that naturally occurs in soybeans.

HPLC Solgen®

– The molecular forms contents in SOLGEN® have been clinically proven to provide high bioavailability.

– EFSA concluded on the absence of adverse effects on breast, uterus and thyroidal gland with the intake of 35-150mg of isoflavones daily through food or supplements.

Clinical studies for
Menopause and Postmenopause

The SOLGEN® family

Delivering the best soybean isoflavones

Depending on the concentration of naturally occurring isoflavones, we have from Solgen®3,
standardized to contain as much as 3% isoflavones to Solgen®80, with the highest concentration of natural soybean isoflavones :

Solgen® Family opens up an array of possibilities in different segments such as dietary supplements, nutritional foods, beverages, and cosmetics.

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